I am on 500 mg metformin XR twice a day and have had nothing but stomach problems since. I run for the bathroom with cramps about 10 times a day and now I have acid reflux all the time. I have never had acid refux before. Can Metformin cause acid reflux? I wind up getting up in the middle of the night with severe reflux that I am taking Pepto Bismol so I can get back to sleep.

Filed under: Acid Reflux

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